Each Serving Size: 1 Tablet film coated tablet contains
Methylcobalamin – 500 mcg
Alpha Lipoic Acid – 100 mg
Benfothiamine – 100 mg
Pyridoxine Hcl – 10 mg
Calcium L-5-Methyltetrahydrofolate -1 mg
Methylcobalamin is one of the active form of vitamin B12 which has role in the formation of myelin sheath and regeneration of nerve. Methylcobalamin is one of the two coenzyme forms of vitamin B12. Evidence indicates this form of vitamin B12, in addition to having a theoretical advantage over cyanocobalamin, Actually has some metabolic and therapeutic applications not shared by the other forms of vitamin B12. Highlight is Methylcobalamin has the potential therapeutic relevance for Bell’s palsy, cancer, diabetic neuropathy, eye function, heart rate variability, HIV, homocysteinemia, male impotence, and sleep disorders.
ALPHA LIPOIC ACID:
Alpha Lipoic Acid is a coenzyme essential for energy production, a superb antioxidant that recycles vitamin C, D and enzymatic antioxidant glutathione. It is anti hyperglycemic which can increase glucose disposal. Reduces Neuropathic symptoms like pain, paresthesia and numbness. Alpha-lipoic acid (ALA) is a powerful natural antioxidant. It has been used to improve diabetic neuropathies and has reduced pain in several studies. Supplementing with Alpha Lipoic Acid for six months has been found to reverse the cause of diabetic nerve damage and improve this painful condition. In double-blind research, 600 mg per day helps reduce nerve damage in people with both Type 1 and Type 2 diabetes (IDDM and NIDDM).
Benfothiamine is a synthetic derivative which is a lipid soluble form of Vitamin B1. Benfothiamine has the ability to inhibit the three major pathways (AGE, PKC & Hexosamine) simultaneously. Hence clinically very useful in preventing the development and progression of Diabetic Complications .Best suitable for therapeutic use owing to its excellent absorption characteristics. Most effective in Small daily doses, either in combination or in monotherapy. Increases the regeneration of nerve cells and folate status has substantial impact on wound care especially in diabetic neuropathy patients.
Pyridoxine (Vitamin B6) is an essential coenzyme in the conversion of the amino acid tryptophan to niacin. Pyridoxine also plays an important role in the body’s metabolism of fats and carbohydrates. The synthesis of unsaturated fatty acids requires pyridoxine. Energy cannot be produced for the cells without this vitamin. Pyridoxine deficiency can cause harm to dendrites, dendrites are the parts of nerve cells that carry impulses from one brain cell to another.
CALCIUM L-5- METHYLTETRAHYDROFOLATE :
Calcium L-5- Methyltetrahydrofolate is the active form of folate which need not be activated by the variants of folate dependent enzymes. Directly absorbed as L-Methylfolate and directly involved in lowering Homocysteine blood levels. The only form of folate able to cross the blood brain barrier with 100 % bioavailability. It is a Hematologic agent (concerned with blood, the blood-forming organs, and blood diseases), which stimulates the hematopoietic system. Childrens, adults and old age require Folic acid to produce healthy red blood cells and prevent anemia. Folate is also essential for the metabolism of homocysteine, and helps maintain normal levels of this amino acid. The human body needs Folate to produce and maintain new cells: it helps to synthesize, repair, It also helps prevent changes to DNA that may lead to cancer. It regenerates the damaged RBC cells in diabetic neuropathy patients. Calcium L-5 Methyltetrahydrofolate is the biologically active form and provides nutritional requirements needed to restore metabolic processes associated with diabetic neuropathy to maintain blood flow by increasing nitric oxide resulting in vasodilatation and regeneration of nerve cells.
No independent and relative contraindication.
No established drug interaction.
Keep in a cool dry place.
One or Two Tablets Daily or as Prescribed by the Healthcare Professional.
Alu Alu Blister pack of 10 tablets