Formulated Dosage Forms

UBIQUE PLUS

COMPOSITION
Each Hard Gelatin Capsule Contains
Ubidecarenone BP 100mg
(Co Enzyme Q 10)
Lycophene USP 2000mcg
L-arginine USP 200mg
Selenium 100mcg

Mechanism of Action and uses
Co Enzyme Q10 is essential co factor in the mitochontrial electron transport chain, where it accepts electron from complex I and II. An activity is the vital for the production of ATP. It also inhibit the oxidation of LDL-Cholestrol, LDL-Cholestrol oxidation is believed to play a significant role in the pathogenesis of atherosclerosis.

Co Enzyme Q10 in the cell membrane may help reduce cell and DNA damage caused by free radicals, which reduces blood pressure and improve egg health, sperm health and in turn embryo quality.

As we age, the ability of the body to produce and metabolize ubiquinone to Ubiquinol declines. In turn so do energy levels and cellular health. This may be due to increased metabolic demand as the body ages, poor nutritional intake, gene mutation, and oxidative stress.
Co Enzyme Q10 used for treating heart and blood vessel conditions such as congestive heart failure (CHF), chest pain (angina), high blood pressure, and heart problems linked to certain cancer drugs. It is also used for diabetes, breast cancer, Huntington’s disease, Parkinson’s disease, muscular dystrophy, increasing exercise tolerance, chronic fatigue syndrome (CFS), and Lyme disease. Some people think coenzyme Q-10 will treat hair loss related to taking warfarin (Coumadin), a medication used to slow blood clotting.

coenzyme Q-10 has a role in producing ATP, a molecule in body cells that functions like a rechargeable battery in the transfer of energy. Coenzyme Q-10 been tried for treating inherited or acquired disorders that limit energy production in the cells of the body (mitochondrial disorders), and for improving exercise performance.

How does it work?
CoQ10 starts off as ubiquinone and then is converted within the cell to the more powerful Ubiquinol. Ubiquinol is considered one of the most powerful antioxidants. Studies have shown that the presence of the most biologically active form of coenzyme Q10 Ubiquinol in the cell membrane may help reduce cell and DNA damage caused by free radicals, which has been shown to reduce blood pressure and improve egg health, sperm health and in turn embryo quality.

Free radicals are unstable molecules that can damage cell structures. In normal everyday life free radicals are produced from the activity in our bodies (for example free radicals are made during ATP synthesis for energy production) but chemicals in our surrounding environment can also create free radicals. It is said that each cell in our body is attacked about 10,000 times a day by free radicals, accelerating the aging process.

Co Enzyme Q10 to Improve Reproductive Health and Boost Fertility
Several diseases associated with infertility and reproductive dysfunction are linked to oxidative stress including endometriosis, unexplained infertility, PCOS, POF, menstrual cycle irregularities, preterm labor, recurrent miscarriage, egg health, sperm health and motility. Several studies show that antioxidant supplementation can reduce oxidative stress, which positively affects the outcome of each of these issues.

Start With Egg and Sperm Health!
In order to have a healthy pregnancy and baby, both the ova and sperm must be healthy! The cells of a developing embryo just after conception cannot divide properly if either ova or sperm health is poor, resulting in miscarriage. If the ova and sperm are very poor in health, conception may not be able to occur, even through IVF.

CoQ10 supplementation may help cells function more normally and divide more normally by restoring normal energy to the mitochondria in each cell. This is very important when considering conception and how the first stages of life are dependent on proper cell division.
Ova (Egg) Health
For women over the age of 35, ovum (egg) health begins to dramatically decline. Once a woman is over 40 years old, ovum health continues to decline and a quickening pace. Each ova is but a single cell, the health of each ova matters greatly. Within each ova is the blueprint of a future child; DNA is the genetic code inherent to the healthy life of a human being yet to be. Ubiquinol has been shown to inhibit DNA oxidation (damage from free radicals), thus protecting the genetic code.

A study published in Fertility and Sterility showed that supplementation of 600 mg of CoQ10 daily by older women improved both egg quality and fertilization rates. Other studies published in Fertility and Sterility also showed the same improvements in the ova of older mice.
A preliminary study of mice by Dr. Robert Casper and colleagues at Samuel Lunenfeld Research Institute, showed that CoQ10 supplementation on mid-aged female mice resulted in more pregnancies and more babies per litter. “They found that when CoQ10 was given to 52-week-old mice – about mid-age for a mouse – their eggs appeared to rejuvenate. There were significantly more egg follicles in the old mice treated with the CoQ10…”

Sperm Count & Health
Just as each ova contains DNA, so does each sperm; the other vital half to the creation of a child. CoQ10 deficiency may lead to not only damaged DNA within the sperm, but low levels affect the ability of sperm to swim, known as motility. Ubiquinol supplementation has a twofold support system for sperm health, one it is protective and second it supports motility by increasing cellular energy.

CoQ10 is found in the highest concentrations inside the mitochondria of all cells. For sperm this is located in the midsection, the area where energy production occurs that powers the tail whip. The higher the blood levels of CoQ10, the greater the sperm’s ability to be strong swimmers. A study in 2009 showed that low levels of CoQ10 in the seminal fluid impacts sperm motility, but supplementation with CoQ10 greatly improved and restored sperm motility in men with very low levels of sperm motility.
One study showed that healthy sperm, with normal morphology (shape), incubated with 50 mg of CoQ10 had a significant increase in sperm motility. That same study also showed that 17 patients with low fertilization rates who supplemented with 60 mg of CoQ10 daily for 103 days had a significant improvement in fertilization rates.

Defective sperm function in infertile men has been shown to be directly associated with increased free radical stress. This is where Ubiquinol supplementation may greatly help to protect sperm health, as well as the health of all the cells that make up the reproductive organs, and the entire body.
Supplementing with Other Antioxidants
For those who want to improve reproductive function, learning how supplementing with “sister” (other types) antioxidants is also important. Ubiquinol is not the only antioxidant that is important to fertility, so are lycophene, l-arginine, selenium Antioxidants rely on one another to revive each other, so each one can continue on protecting cellular health and function. While Ubiquinol is considered the most powerful of all antioxidants, these other antioxidants play their own important key role in proper function of the body, including egg and sperm health.

LYCOPHENE
Lycophene acts as antioxidant by fighting free radicals in the body. Due to its antioxidant property, it reduces the risk of cancer , cardiovascular diseases, fertility disorders.lycophene prevents heart diseases, hardening of the arteries, cancer of the prostate, breast, lung, ovaries, colon, and pancrease.

L-ARGININE
L-arginine is a chemical building block called “an amino acid.” L-arginine is converted in the body into a chemical called nitric oxide. Nitric oxide causes blood vessels to open wider for improved blood flow. L-arginine also stimulates the release of growth hormone, insulin, and other substances in the body.

L-arginine is used for heart and blood vessel conditions including congestive heart failure (CHF), chest pain, high blood pressure, and coronary artery disease. L-arginine is also used for recurrent pain in the legs due to blocked arteries (intermittent claudication), decreased mental capacity in the elderly (senile dementia), erectile dysfunction (ED), and male infertility. L-arginine also improves sperm count and motility. L-arginine also improves sexual desire and ejaculation.

SELENIUM
L-arginine and selenium added to a low-calorie diet enriched with legumes regulates cardiovascular risk factors in women with central obesity. selenium deficiency lowers the reproduction rates in man as well as in animals. Selenium is needed for production of testosterone. When selenium levels are low, sperm are immobile because the tail is weakened or deformed. In men, selenium is essential for sperm production-almost half of the male body’s supply of selenium is concentrated in the testicles and the seminal ducts adjacent to the prostate gland.

Selenium is an antioxidant that prevents free-radical damage, works synergistically with vitamin E, and preserves tissue elasticity. Drug Interaction
CO ENZYME Q 10 is known to interact with other drugs like captopril, enlapril, losartan, valsartan, diltiazem, amlodipine, warfarfin,

Side Effects
No Significant Disorders

Presentation & Packing
10 capsules in Alu Alu Packing.

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